Yes, Kelsey Grammer is coming back to television. But if you're looking for another Frasier Crane, check out his reruns on Lifetime.

With the new Fox series "Back to You," Grammer's got a brand-new bag as the blusterous Chuck Darling, an anchorman whose big-market career and over-inflated ego take a hit when he winds up back at the struggling station in Pittsburgh where he started.

Of course, there's one thing about Darling that's remotely reminiscent of that other baritone-voiced guy — the man who plays him.

"On a daily basis, we say, 'OK, what would Frasier do here, and let's do the opposite,' " says Steven Levitan, series co-creator with fellow "Frasier" alum Christopher Lloyd. "We hope in time that they will see him as Chuck Darling. I know we have."

Explains Grammer: "Chuck is really a simpleton. He's not the smartest guy in the world — smart enough to get by, not a bad storyteller, but he's an egomaniac where Frasier was not."

Comedy in the series, which makes its debut on Sept. 19, comes from the clash of egos between Darling and former co-anchor Kelly Carr (Patricia Heaton), who is less than thrilled to be sharing the news desk with him.

On the set, however, there's a sense of genuine camaraderie between Grammer and fellow sitcom vet Heaton ("Everybody Loves Raymond") as they finesse their way through each scene.

"What makes Patty so important to us is that she's one of those rare actresses who can go toe-to-toe with Kelsey, who can be just as strong as he is in a way that doesn't make her seem unlikable," Levitan says. "From the beginning, Kelsey locked into Patricia as the right person for that role."

It didn't hurt that the two shared the same agent and had been looking for a chance to work together.

The series gave both actors a chance to return to television in the format they love: the multi-camera sitcom, which is presented like a play before a live audience. The genre also offers amenable hours because each episode is shot primarily in one night — a plus for Heaton, who's raising four boys.

For Grammer, 52, it was a chance to reunite with Lloyd and Levitan.

While he's aware that sitcom successes like "Frasier" and "Raymond" are rare and getting rarer, and that stars of long-running sitcoms seem to fail more often than not in subsequent efforts, Grammer isn't deterred.

"Multi-camera for me is the only world that is really funny," he says. "Single-camera shows are entertaining and thought-provoking, sometimes humorous. But fall down laughing out loud shows? No, I don't see it."

Although Fox recently tried its hand at another series about TV news — the unscripted "Anchorwoman," which flopped in its first week — Heaton believes the scripted anchors on "Back to You" will offer a more entertaining show.

"You know, I was surprised when Fox put that other show on when we're on the network, too — so I was sort of glad it was pulled," says Heaton.

Besides, she adds, "So much of (the news business) is entertainment anyway, the logos and the drama and the crisis, anything to get eyes is what it is."