TONIGHT'S MUST-SEE

"Show Me the Money" (8:30 p.m., ABC) and/or "3 lbs" (9 p.m., CBS). Two shows premiere tonight, one of them dead serious. The light one is on ABC. It includes William Shatner, dancing girls, trivia questions and prizes. The other is "3 lbs," set in a New York hospital that would be crumbling if it weren't for its neurosurgery unit. In charge is Doug Hanson — intense, precise, brilliant, not a people person. He's played by Stanley Tucci, whose great work has ranged from fierce villains to the benevolent Nigel in "The Devil Wears Prada." The people part is provided by his new protege (Mark Feuerstein) and by a warm and barefoot neurologist (Indira Varma, who was Niobe in "Rome"). Tucci is terrific, and this show captures some of the "House" skills. Still, we'll have to wait to see if brain surgery is too limited a turf for a weekly season.

OF NOTE

"Dancing with the Stars," 7 p.m., ABC. Here's the final face-off. Then voters have their say, with the winner being announced on Wednesday.

"Friday Night Lights," 7 p.m., NBC. The homecoming game nears, with an undefeated opponent coming. That brings the return of a former star, carrying a secret. Meanwhile, Tim Riggins tries to give up drinking, while clinging to his own secret affair with his paralyzed friend's girlfriend.

"Nova: The Family That Walks on All Fours," 8 p.m., PBS. A Turkish family has been found in which five siblings instinctively walk on all fours. Scientists disagree about whether this is a genetic throwback.

"House," 8 p.m., Fox. Last week, Dr. Wilson learned that Dr. House stole his prescription pad and forged his name. Now comes a confrontation between friends. Wilson lied for House when questioned by Tritter (David Morse), the police detective. Tonight, however, Tritter is relentless; all of that complicates a complex case, with John Larroquette in a guest role.

"Law & Order: Special Victims Unit," 9 p.m., NBC. Three teen murder victims have identical tattoos, leading to a broader investigation.