TONIGHT'S MUST-SEE

"Prison Break" and "Justice," 7 and 8 p.m., Fox. It's a strong night. In "Prison Break," the escapees have the $5 million now — but one of them grabs it all for himself. Meanwhile, Mahone faces questions about the deaths of Abruzzi and Tweener. Sara is in danger, and Linc is trying to find a way to get his son back. Then "Justice" has the firm defending a teen outsider in the ritualistic killing of a school bully.

"American Experience: Test Tube Babies," 9 p.m., PBS. A generation ago, test-tube fertilization was fiercely controversial. In 1973, a hospital official in New York seized a fertilized egg in a lab and destroyed it. Then views changed, this fascinating documentary says. Now, 400,000 Americans and 2 million people worldwide have been created by in vitro fertilization.

OF NOTE

"Why I Wore Lipstick to My Mastectomy," 6 p.m., Lifetime. Geralyn Lucas was 27 when she was diagnosed with breast cancer. Lucas, a Lifetime executive, wrote a book about the experience; it's been turned into a movie, mixing comedy with the drama; Sarah Chalke ("Scrubs") stars.

"How I Met Your Mother," 7 p.m., CBS. Two guest stars show up: Jane Seymour is Marshall's professor; Barney schemes to seduce her. Bryan Cranston is Ted's boss; Lily wants to teach him a lesson.

"The Class," 7:30 p.m., CBS. Richie and Duncan are accompanying Yonk, the retired football star, to a fan session in Atlantic City; Nicole, Yonk's wife, wants the guys to keep him from gambling.

"Heroes," 8 p.m., NBC. Hiro is jumped by some big-time gamblers in Las Vegas. Meanwhile, Niki faces another time gap, and Matt finds it's really quite useful to read his wife's mind.